ea0011p489 | Endocrine tumours and neoplasia | ECE2006
Johnsen I
, Hahner S
, Fassnacht M
, Bertherat J
, Bertagna X
, Plouin PF
, Reincke M
, Allolio B
, Beuschlein F
Tissue samples from adrenal tumors provide the basis for standard diagnostic procedures such as pathological examination. In addition, these tumor samples have been an invaluable source for the discovery of novel molecular pathways involved in adrenal tumorigenesis. Information on the molecular phenotype are based on DNA mutation analysis and epigenetic changes, RNA and protein expression pattern and sub-cellular localization as well as post transcriptional protein modificatio...